Unlike traditional financial markets, cryptocurrency exchanges allow investors the ability to trade any day of the week. For the past couple of years, however, trading on the weekends has not been as prevalent, with user activity being the weakest on Saturdays and Sundays across all the top exchanges.

*BTC-USD volume, except for Binance which used BTC-USDT volume
Source: CoinAPI, BitDealer, The Block
Since the beginning of the year, aggregate BTC trade volumes at the top five exchanges vetted by Bitwise (Binance, Coinbase, Bitfinex, Bitstamp, and Kraken) have exceeded $20 billion for each weekday, with Wednesday having the highest with $28.4 billion aggregate volume.